Key Elements For Tissue And Organ Regeneration - 1830 Words

Introduction Tissue engineering is an interdisciplinary approach that basically replaces, restore the function and regenerate the damaged cell or tissue using biological substitutes. Succinctly, extracellular matrix (ECM) in human tissue is a key element for tissue and organ regeneration. It provides a convenient environment for the cellular attachment, growth and migration stimulate by specific signals. This solid matrix has a complex mixture of structural and functional proteins that serve as a reliable source of nutrient for the cells. ECM also associated with the cell behaviour, tissue differentiation, organisation and neovascularisation. In tissue engineering, the suitable scaffolds are use to act as an ECM analogue (1). The various roles and complicated composition of ECM become a great challenge for the scaffolds to mimic the native ECM in repairing the diseased or damaged tissue. Thus, it is important to develop the ideal scaffolds with optimal properties and architecture since its mechan ical characteristics will greatly affect the activity of cell adhesion, proliferation and differentiation. Apparently, the biomaterial used in fabrication of scaffolds may influence its significant features, such as biodegradability, bioactivity and porosity. The bioactivity, including cell adhesion, cell alignment and interaction between scaffolds and cellular components could be enhanced by adding the biological cues onto the biomaterials. Besides that, it is also important forShow MoreRelatedInvestigating And Determine Compatible Naturally Based Elements That Can Potentially Replace And Be Integrated Into The Bone Tissue Essay1538 Words   |  7 PagesThe objective of this project is to investigate and determine compatible naturally based elements that can potentially replace and be integrated into the bone tissue, for medical purposes. These elements should be similar in characteristic and structure of the bone tissue, so that they can effectively replace the tissue and help stimulate bone growth and cellular growth, in order to maintain bone homeostasis. In order to achieve compatib ility, factors such as 3-D polymeric structures within boneRead MoreEndocrine Systems : The Endocrine System1170 Words   |  5 Pagesglands. The Hypothalamus gland regulates hunger, thirst, sleep and wakefulness, along with most of your involuntary mechanisms, including body temperature. The Pituitary gland controls all other endocrine glands, it influences growth metabolism and regeneration. The Thyroid gland regulates your energy and your metabolism. The Parathyroid gland secretes the hormones necessary for calcium absorption. The Thymus gland helps build resistance to disease. 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Regional anatomy – considers all of the superficial and internal features in a specific region of the body. Systemic Anatomy – considers structures of the major organ systems. Human Physiology – study of functions of human body Cell Physiology –Read MoreA Model Organism Is A Non Human Species1947 Words   |  8 Pageselucidate new mechanisms for understanding cancer and cell regeneration. Imaging studies enable non-invasive study of human subjects. Recent advances in genetics and genomics can identify disease-associated genes, which can be targeted for therapies. Important model organisms Among vertebrates, the rat is particularly useful as a toxicology model, and as a neurological model and source of primary cell cultures, owing to the larger size of organs and suborganellar structures relative to the mouse, whileRead MoreThe Effects of Smoking 2118 Words   |  8 Pagesand over 50 human carcinogens. The toxins in cigarette smoke include carbon monoxide, hydrogen cyanide, and methyl- isocyanate (Yarkony, 1993). The cigarette smoke contains nitrosamines, which cause cancer of the lung, respiratory system, and other organs; aromatic amines, which lead to the bladder and breast cancer; formaldehyde, which bring about nasal cancer; and benzene, which induce leukemia. Smoking also affects pregnant woman very badly. Developmental growth and birth weight in babies of smokingRead MoreFactors Affecting Plant Growth And Development7928 Words   |  32 Pagestranspiration rate under water deficit by improving size, architecture, and hydraulic conductance of root system or a r eduction of transpiration by stomatal closure or leaf area reduction[401]. Water availability influences the morphology of several organs of plants and some physiological and biochemical characteristics. Flower corolla length and lifespan was related to precipitation in Ruellia subsessilis[284], root tips and green needle proportion were decreased[291], and root surface area was negativeRead MoreThe Effect of Inflation in Ethiopia6723 Words   |  27 Pagesand aiming radiation sources so as to best affect cancerous tissue without affecting the neighboring healthy tissue. Prior to VR, most doctors used radiation 16 projected only along x, y, and z axes, since that was the easiest to visualize and calculate. By experimenting with a see-through patient in a virtual environment, doctors are able to better determine optimal, often oblique radiation angles, yielding less damage to healthy tissue and faster recovery times. Biochemical engineers might apply